Studies and evaluation in Pharmacodynamics and Toxicology, adhering to international norms and standards, to provide reference support to the development of pharmaceutical products by Brazilian companies and R&D institutions.
Development of toxicological trials (acute and chronic) in rodents and non-rodents)
These experiments are conducted according to the recommendations of the leading international agencies.
Identification of potential adverse reactions
Realization of studies needed to evaluate the occurrence of adverse events, related to the medication.
Studies of pharmacokinetics and toxicokinetics
Trials are performed involving analyses of high-performance and mass spectrometry for the characterization of absorption, distribution, metabolism and elimination of pharmaceuticals.
Mechanism of action studies
The Center of Pre-Clinical Pharmacology executes classic protocols or those with modern cellular and molecular biology techniques, and uses transgenic animals to evaluate the mechanism of action of compounds, and to identify new therapeutic targets. To do so, it has its own animal breeding laboratory and international standard facilities.
The Pre-Clinical Pharmacology Center offers consulting services to pharmaceutical companies, related to the realization of research needed to register medications.